Fev^tm2.1Esd
Targeted Allele Detail

Summary

• Symbol: Fev^tm2.1Esd
• Name: FEV transcription factor, ETS family member; targeted mutation 2.1, Evan S Deneris
• MGI ID: MGI:4837198
• Synonyms: Pet-1^delta
• Gene: Fev Location: Chr1:74920668-74924578 bp, - strand
• Alliance: Fev^tm2.1Esd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165266
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: LoxP sites were inserted in around exon 3 via homologous recombination. Cre mediated recombination removed exon 3. (J:165266)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fev Mutation: 14 strains or lines available

References

• Original: J:165266 Liu C, et al., Pet-1 is required across different stages of life to regulate serotonergic function. Nat Neurosci. 2010 Oct;13(10):1190-8
• All: 1 reference(s)