Nbr1^tm1.1Jmos
Targeted Allele Detail

Summary

• Symbol: Nbr1^tm1.1Jmos
• Name: NBR1, autophagy cargo receptor; targeted mutation 1.1, Jorge Moscat
• MGI ID: MGI:4837426
• Synonyms: NBR1^fl
• Gene: Nbr1 Location: Chr11:101442975-101472777 bp, + strand Genetic Position: Chr11, 65.36 cM
• Alliance: Nbr1^tm1.1Jmos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165438
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT flanked neo cassette with a 5' loxP site was inserted upstream of exon 5 and an additional loxP site was inserted downstream of exon 5. Flp mediated recombination removed the neo cassette leaving exon 5 floxed. (J:165438)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nbr1 Mutation: 74 strains or lines available

References

• Original: J:165438 Yang JQ, et al., NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo. EMBO J. 2010 Oct 6;29(19):3421-33
• All: 4 reference(s)