Tg(Pdgfra-cre)1Clc
Transgene Detail

Summary

• Symbol: Tg(Pdgfra-cre)1Clc
• Name: transgene insertion 1, Constance L Cepko
• MGI ID: MGI:4837746
• Synonyms: Pdgfra-CRE BAC, PDGFRalpha-CRE
• Transgene: Tg(Pdgfra-cre)1Clc Location: unknown
• Alliance: Tg(Pdgfra-cre)1Clc page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pdgfra-cre)1Clc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pdgfra (MGI:97530)

• Mutation details: A cre recombinase gene, SV40 late polyA site, and an-FRT-flanked kanamycin cassette were introduced 3' of the Pdgfra promoter in mouse BAC RP23-116F7. The kanamycin cassette was excised from the vector and the linearized BAC was injected into C57BL/6 blastocysts. This strain was maintained on a C57BL/6 genetic background by the donating laboratory. (J:165545)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdgfra (mouse) Summary of all recombinase alleles driven by Pdgfra. Comparative matrix view of recombinase activities Alliance mouse Pdgfra gene page

Disease models

Expression

In Mice Carrying this Mutation:

6 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:165545 Roesch K, et al., The transcriptome of retinal Muller glial cells. J Comp Neurol. 2008 Jul 10;509(2):225-38
• All: 95 reference(s)