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Tlr8/Tlr7tm1Vlcg
Targeted Allele Detail
Summary
Symbol: Tlr8/Tlr7tm1Vlcg
Name: toll-like receptor 8; targeted mutation 1, Velocigene
MGI ID: MGI:4837832
Gene: Tlr8  Location: ChrX:166025692-166047325 bp, - strand  Genetic Position: ChrX, 78.29 cM, cytoband F5
Alliance: Tlr8/Tlr7tm1Vlcg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165267
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intergenic deletion
  Tlr8/Tlr7tm1Vlcg involves 2 genes/genome features (Tlr8, Tlr7) View all
 
Mutation detailsMost of the coding region of each gene as well as the 70 kb interveining sequence was replaced with a lacZ gene. (J:102090)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tlr8 Mutation:  10 strains or lines available
Notes
Embryonic stem cells used to generate this allele are either CJ7 (129S1/Sv), F1H4 ((129 x C57BL/6)/F1), RW4 (129X1/SvJ), or an unnamed C57BL/6 line. (J:102090)
References
Original:  J:102090 Valenzuela DM, et al., High-throughput engineering of the mouse genome coupled with high-resolution expression analysis. Nat Biotechnol. 2003 Jun;21(6):652-9
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory