Ccn2^tm1Mae
Targeted Allele Detail

Summary

• Symbol: Ccn2^tm1Mae
• Name: cellular communication network factor 2; targeted mutation 1, Nobuyo Maeda
• MGI ID: MGI:4838151
• Gene: Ccn2 Location: Chr10:24471340-24474581 bp, + strand Genetic Position: Chr10, 11.84 cM, cytoband A3-B1
• Alliance: Ccn2^tm1Mae page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165111
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin selection cassette replaced all of exons 3 through 5. (J:165111)

Expression

In Mice Carrying this Mutation:

3 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ccn2 Mutation: 29 strains or lines available

References

• Original: J:165111 Doherty HE, et al., A mouse strain where basal connective tissue growth factor gene expression can be switched from low to high. PLoS One. 2010;5(9):e12909
• All: 2 reference(s)