Rlim^tm1.1Inba
Targeted Allele Detail

Summary

• Symbol: Rlim^tm1.1Inba
• Name: ring finger protein, LIM domain interacting; targeted mutation 1.1, Ingol Bach
• MGI ID: MGI:4838153
• Synonyms: Rnf12^fl
• Gene: Rlim Location: ChrX:103000770-103024886 bp, - strand Genetic Position: ChrX, 46.42 cM, cytoband D
• Alliance: Rlim^tm1.1Inba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165550
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The coding region of exon 5 was floxed and a neo cassette with a 3' loxP site was inserted downstream of the stop codon. Cre mediated recombination removed the neo cassette leaving the coding region of exon 5 floxed. (J:165550)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rlim Mutation: 18 strains or lines available

References

• Original: J:165550 Shin J, et al., Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature. 2010 Oct 21;467(7318):977-81
• All: 6 reference(s)