Rbfox1^tm1.1Dblk
Targeted Allele Detail

Summary

• Symbol: Rbfox1^tm1.1Dblk
• Name: RNA binding protein, fox-1 homolog (C. elegans) 1; targeted mutation 1.1, Douglas Black
• MGI ID: MGI:4838179
• Synonyms: Fox-1^flox, Rbfox1^loxP
• Gene: Rbfox1 Location: Chr16:5703219-7229390 bp, + strand Genetic Position: Chr16, 3.34 cM
• Alliance: Rbfox1^tm1.1Dblk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165698
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert loxP sites flanking exons 11-12 of the RNA binding protein, fox-1 homolog 1 (Rbfox1) gene, followed by a frt-flanked neomycin resistance (neo) cassette. Flp-mediated recombination removed the neo cassette leaving exons 11 and 12 floxed. (J:165698)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rbfox1 Mutation: 33 strains or lines available

References

• Original: J:165698 Black D, Direct Data Submission 2010/11/09. MGI Direct Data Submission. 2010
• All: 12 reference(s)