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Wnt4tm1.2Boer
Targeted Allele Detail
Summary
Symbol: Wnt4tm1.2Boer
Name: wingless-type MMTV integration site family, member 4; targeted mutation 1.2, Derek Boerboom
MGI ID: MGI:4838181
Synonyms: Wnt4-
Gene: Wnt4  Location: Chr4:137004946-137026812 bp, + strand  Genetic Position: Chr4, 69.8 cM
Alliance: Wnt4tm1.2Boer page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:162337
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA genomic segment spanning exon 3 and exon 4 was removed by crossing Wnt4tm1.1Boer with cre deleter mice. This is a null allele. (J:162337)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt4 Mutation:  21 strains or lines available
References
Original:  J:162337 Boyer A, et al., WNT4 is required for normal ovarian follicle development and female fertility. FASEB J. 2010 Aug;24(8):3010-25
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory