Rbfox2^tm1.1Dblk
Targeted Allele Detail

Summary

• Symbol: Rbfox2^tm1.1Dblk
• Name: RNA binding protein, fox-1 homolog (C. elegans) 2; targeted mutation 1.1, Douglas Black
• MGI ID: MGI:4838182
• Synonyms: Fox-2^flox, Rbfox2^loxP
• Gene: Rbfox2 Location: Chr15:76963190-77191204 bp, - strand Genetic Position: Chr15, 36.4 cM, cytoband E1
• Alliance: Rbfox2^tm1.1Dblk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165699
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert loxP sites flanking exons 6-7 of the RNA binding protein, fox-1 homolog 2 (Rbfox2) gene, followed by a FRT-flanked neomycin resistance (neo) cassette. Flp-mediated recombination removed the neo cassette and left exons 6 and 7 floxed. (J:165699)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	21 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rbfox2 Mutation: 81 strains or lines available

References

• Original: J:165699 Black D, Direct Data Submission 2010/11/09. MGI Direct Data Submission. 2010
• All: 12 reference(s)