Cd226^tm1Shib
Targeted Allele Detail

Summary

• Symbol: Cd226^tm1Shib
• Name: CD226 antigen; targeted mutation 1, Akira Shibuya
• MGI ID: MGI:4838287
• Gene: Cd226 Location: Chr18:89195091-89290353 bp, + strand Genetic Position: Chr18, 59.05 cM
• Alliance: Cd226^tm1Shib page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165704
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a neo cassette. Flow cytometry confirmed the absence of spleen cells expressing the protein. (J:165704)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd226 Mutation: 34 strains or lines available

References

• Original: J:165704 Iguchi-Manaka A, et al., Accelerated tumor growth in mice deficient in DNAM-1 receptor. J Exp Med. 2008 Dec 22;205(13):2959-64
• All: 10 reference(s)