Col13a1^tm3.1Pih
Targeted Allele Detail

Summary

• Symbol: Col13a1^tm3.1Pih
• Name: collagen, type XIII, alpha 1; targeted mutation 3.1, Taina Pihlajaniemi
• MGI ID: MGI:4838409
• Synonyms: Col13a1^T
• Gene: Col13a1 Location: Chr10:61674015-61814887 bp, - strand Genetic Position: Chr10, 32.29 cM, cytoband B4
• Alliance: Col13a1^tm3.1Pih page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:164671
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a floxed neo cassette. Cre mediated recombination removed the neo cassette. The absence of protein expression was confirmed by western blot analysis on lung and femur extracts. (J:164671)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Col13a1 Mutation: 70 strains or lines available

References

• Original: J:164671 Latvanlehto A, et al., Muscle-derived collagen XIII regulates maturation of the skeletal neuromuscular junction. J Neurosci. 2010 Sep 15;30(37):12230-41
• All: 5 reference(s)