Caprin1^tm1Mtok
Targeted Allele Detail

Summary

• Symbol: Caprin1^tm1Mtok
• Name: cell cycle associated protein 1; targeted mutation 1, Makio Tokunaga
• MGI ID: MGI:4838547
• Synonyms: RNG105^-
• Gene: Caprin1 Location: Chr2:103593292-103627946 bp, - strand Genetic Position: Chr2, 54.43 cM
• Alliance: Caprin1^tm1Mtok page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:164650
• Parent Cell Line: IT2 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on E17.5 embryo extracts. (J:164650)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Caprin1 Mutation: 51 strains or lines available

References

• Original: J:164650 Shiina N, et al., RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks. J Neurosci. 2010 Sep 22;30(38):12816-30
• All: 2 reference(s)