Tg(Pdx1-cre)PBMga
Transgene Detail

Summary

• Symbol: Tg(Pdx1-cre)PBMga
• Name: transgene insertion PB, Maureen A Gannon
• MGI ID: MGI:4839473
• Synonyms: Pdx1^PBCre
• Transgene: Tg(Pdx1-cre)PBMga Location: unknown
• Alliance: Tg(Pdx1-cre)PBMga page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pdx1-cre)PBMga expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Pdx1

• Mutation details: A 1 kb Pst2-BstEI fragment (Pdx1) containing areas I and II of the Pdx1 gene was fused to the Hsp68 minimal promoter to drive expression of a cre/hGH fusion cDNA. One line was generated. (J:72023, J:122333)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdx1 (species not specified) Summary of all recombinase alleles driven by Pdx1.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:122333 Wiebe PO, et al., Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression. Mol Cell Biol. 2007 Jun;27(11):4093-104
• All: 4 reference(s)