Cbln1^tm1.1Mmsh
Targeted Allele Detail

Summary

• Symbol: Cbln1^tm1.1Mmsh
• Name: cerebellin 1 precursor protein; targeted mutation 1.1, Masayoshi Mishina
• MGI ID: MGI:4839623
• Gene: Cbln1 Location: Chr8:88195481-88199220 bp, - strand Genetic Position: Chr8, 42.16 cM
• Alliance: Cbln1^tm1.1Mmsh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165995
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 1 and an additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette leaving exon 1 and 2 floxed. (J:165995)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cbln1 Mutation: 15 strains or lines available

References

• Original: J:165995 Uemura T, et al., Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum. Cell. 2010 Jun 11;141(6):1068-79
• All: 2 reference(s)