Terf2ip^tm1.1Blas
Targeted Allele Detail

Summary

• Symbol: Terf2ip^tm1.1Blas
• Name: telomeric repeat binding factor 2, interacting protein; targeted mutation 1.1, Maria A Blasco
• MGI ID: MGI:4839729
• Synonyms: Rap1^flox
• Gene: Terf2ip Location: Chr8:112738030-112747160 bp, + strand Genetic Position: Chr8, 58.29 cM
• Alliance: Terf2ip^tm1.1Blas page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165984
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 3 and an additional loxP site was inserted downstream of exon 3. Flp mediated recombination removed the neo cassette leaving exon 3 floxed. (J:165984)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Terf2ip Mutation: 31 strains or lines available

References

• Original: J:165984 Martinez P, et al., Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites. Nat Cell Biol. 2010 Aug;12(8):768-80
• All: 1 reference(s)