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Emg1tm1Hdin
Targeted Allele Detail
Summary
Symbol: Emg1tm1Hdin
Name: EMG1 N1-specific pseudouridine methyltransferase; targeted mutation 1, Hao Ding
MGI ID: MGI:4839753
Gene: Emg1  Location: Chr6:124681344-124689118 bp, - strand  Genetic Position: Chr6, 59.17 cM
Alliance: Emg1tm1Hdin page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165972
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 through 6 were replaced with a splice acceptor, IRES, and beta-geo cassette. Whole mount in situ confirmed beta-galactosidase activity. (J:165972)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 30 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Emg1 Mutation:  23 strains or lines available
References
Original:  J:165972 Wu X, et al., EMG1 is essential for mouse pre-implantation embryo development. BMC Dev Biol. 2010;10:99
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory