Emg1^tm1Hdin
Targeted Allele Detail

Summary

• Symbol: Emg1^tm1Hdin
• Name: EMG1 N1-specific pseudouridine methyltransferase; targeted mutation 1, Hao Ding
• MGI ID: MGI:4839753
• Gene: Emg1 Location: Chr6:124681344-124689118 bp, - strand Genetic Position: Chr6, 59.17 cM
• Alliance: Emg1^tm1Hdin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165972
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 6 were replaced with a splice acceptor, IRES, and beta-geo cassette. Whole mount in situ confirmed beta-galactosidase activity. (J:165972)

Expression

In Mice Carrying this Mutation:	30 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Emg1 Mutation: 23 strains or lines available

References

• Original: J:165972 Wu X, et al., EMG1 is essential for mouse pre-implantation embryo development. BMC Dev Biol. 2010;10:99
• All: 1 reference(s)