Gldn^tm1Pele
Targeted Allele Detail

Summary

• Symbol: Gldn^tm1Pele
• Name: gliomedin; targeted mutation 1, Elior Peles
• MGI ID: MGI:4840020
• Gene: Gldn Location: Chr9:54193770-54249061 bp, + strand Genetic Position: Chr9, 29.52 cM
• Alliance: Gldn^tm1Pele page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166099
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 9 and 10 were replaced with an FRT-flanked neo cassette. The absence of protein expression was confirmed by western blot analysis on sciatic nerve lysates. (J:166099)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gldn Mutation: 26 strains or lines available

References

• Original: J:166099 Feinberg K, et al., A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier. Neuron. 2010 Feb 25;65(4):490-502
• All: 3 reference(s)