Tg(Zic4-icre)1Kess
Transgene Detail

Summary

• Symbol: Tg(Zic4-icre)1Kess
• Name: transgene insertion 1, Nicoletta Kessaris
• MGI ID: MGI:4840322
• Synonyms: Zic4-Cre^Tg
• Transgene: Tg(Zic4-icre)1Kess Location: unknown
• Alliance: Tg(Zic4-icre)1Kess page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Zic4-icre)1Kess expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Zic4

• Mutation details: The codon-improved cre sequence (icre) containing a nuclear localization signal was fused to the initiation codon of the Zic4 gene located in a BAC. The icre sequence was followed by the simian SV40 polyA signal and an Frt-flanked kanamycin selection cassette. The selection cassette was removed from the construct before injection inot fertilized eggs. Number of founder animals and line numbers are not available. (J:164291)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Zic4 (species not specified) Summary of all recombinase alleles driven by Zic4. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:164291 Rubin AN, et al., The germinal zones of the basal ganglia but not the septum generate GABAergic interneurons for the cortex. J Neurosci. 2010 Sep 8;30(36):12050-62
• All: 9 reference(s)