TgTn(pb-sb-ATP1)S2Brd
Transgene Detail

Summary

• Symbol: TgTn(pb-sb-ATP1)S2Brd
• Name: transgenic transposon concatemer S2, Allan Bradley
• MGI ID: MGI:4840493
• Synonyms: ATP1-S2
• Transgene: TgTn(pb-sb-ATP1)S2Brd Location: unknown Genetic Position: Chr10, Syntenic
• Alliance: TgTn(pb-sb-ATP1)S2Brd page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Transposon concatemer)
• Mutation: Insertion
• Mutation details: This transgene consists of PiggyBac and Sleeping Beauty inverted terminal repeats flanking (in order) a carp beta actin splice acceptor, two bidirectional SV40 polyadenylation signals, the CAG (cytomegalovirus enhancer and chicken beta-actin) promoter, the Foxf2 exon 1 splice donor and an inverted Engrailed 2 exon 2 splice acceptor. The PiggyBac and Sleeping Beauty terminal repeats are inverted relative to each other. This line contains 20 copies of the transgene inserted into chromosome 10. (J:166063)

Tumor Data

List all tumor models in MMHCdb carrying TgTn(pb-sb-ATP1)S2Brd

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:166063 Rad R, et al., PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice. Science. 2010 Nov 19;330(6007):1104-7
• All: 3 reference(s)