Csl^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Csl^{tm1(KOMP)Vlcg}
• Name: citrate synthase like; targeted mutation 1, Velocigene
• MGI ID: MGI:4842999
• Synonyms: eCs-KO
• Gene: Csl Location: Chr10:99593567-99595346 bp, - strand Genetic Position: Chr10, 51.2 cM, cytoband C3
• Alliance: Csl^{tm1(KOMP)Vlcg} page
• IMPC: Csl gene page

Mutation origin

• Mutant Cell Lines: 14519A-B9, 14519A-B11, 14519A-G2, 14519A-G5
• Germline Transmission: Earliest citation of germline transmission: J:287403
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1557bp between positions 99593504-99595060 of Chromosome 10 (Build GRCm39). (J:136110)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Csl Mutation: 17 strains or lines available

Notes

Cell line 14519A-G5 was successfully used to make chimeric mice. Germline transmission was accomplished. J:287403

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 6 reference(s)