Klk7^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Klk7^{tm1(KOMP)Vlcg}
• Name: kallikrein related-peptidase 7 (chymotryptic, stratum corneum); targeted mutation 1, Velocigene
• MGI ID: MGI:4843047
• Gene: Klk7 Location: Chr7:43460718-43465783 bp, + strand Genetic Position: Chr7, 28.27 cM, cytoband B2
• Alliance: Klk7^{tm1(KOMP)Vlcg} page
• IMPC: Klk7 gene page

Mutation origin

• Mutant Cell Lines: 14816A-B7, 14816A-B9, 14816A-C5, 14816A-E5, 14816A-H10
• Germline Transmission: Earliest citation of germline transmission: J:261970
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 3567bp between positions 43461388-43464954 of Chromosome 7 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Klk7 Mutation: 13 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)