Atp11c^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Atp11c^m1Btlr
• Name: ATPase, class VI, type 11C; mutation 1, Bruce Beutler
• MGI ID: MGI:4843273
• Synonyms: emptyhive
• Gene: Atp11c Location: ChrX:59268643-59450041 bp, - strand Genetic Position: ChrX, 33.5 cM, cytoband A5
• Alliance: Atp11c^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation corresponds to a C to T transition at nucleotide position 2113 of the transcript that replaces a triplet encoding glutamine to a termination codon at amino acid position 655 (Q655Ter). (J:171925)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atp11c Mutation: 16 strains or lines available

References

• Original: J:171925 Siggs OM, et al., The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow. Nat Immunol. 2011 May;12(5):434-40
• All: 4 reference(s)