Atp11c^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Atp11c^m2Btlr
• Name: ATPase, class VI, type 11C; mutation 2, Bruce Beutler
• MGI ID: MGI:4843275
• Synonyms: spelling
• Gene: Atp11c Location: ChrX:59268643-59450041 bp, - strand Genetic Position: ChrX, 33.5 cM, cytoband A5
• Alliance: Atp11c^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation, in the 12th of the gene's 30 exons, corresponds to a T to A transversion at nucleotide position 1214 of the transcript that is predicted to replace isoleucine with lysine at amino acid position 355 of the protein (I355K). (J:171925)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atp11c Mutation: 16 strains or lines available

References

• Original: J:171925 Siggs OM, et al., The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow. Nat Immunol. 2011 May;12(5):434-40
• All: 3 reference(s)