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Slc34a2tm1.1Scc
Targeted Allele Detail
Summary
Symbol: Slc34a2tm1.1Scc
Name: solute carrier family 34 (sodium phosphate), member 2; targeted mutation 1.1, Susan S Schiavi
MGI ID: MGI:4847567
Synonyms: Npt2bfl
Gene: Slc34a2  Location: Chr5:53206695-53229006 bp, + strand  Genetic Position: Chr5, 28.92 cM
Alliance: Slc34a2tm1.1Scc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166317
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP flanked neo cassette was inserted upstream of exon 6, and an additional loxP site was inserted downstream of exon 6. Cre-mediated recombination removed the neo cassette leaving exon 6 floxed. (J:166317)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc34a2 Mutation:  41 strains or lines available
Notes
ES cell line = AMK06.
References
Original:  J:166317 Sabbagh Y, et al., Intestinal npt2b plays a major role in phosphate absorption and homeostasis. J Am Soc Nephrol. 2009 Nov;20(11):2348-58
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory