Tac4^tm1Albe
Targeted Allele Detail

Summary

• Symbol: Tac4^tm1Albe
• Name: tachykinin 4; targeted mutation 1, Alexandra Berger
• MGI ID: MGI:4847657
• Gene: Tac4 Location: Chr11:95152355-95160091 bp, + strand Genetic Position: Chr11, 59.01 cM
• Alliance: Tac4^tm1Albe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166471
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2, which contains the entire peptide, was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on olfactory epithelium. (J:166471)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tac4 Mutation: 10 strains or lines available

References

• Original: J:166471 Berger A, et al., Targeted deletion of the tachykinin 4 gene (TAC4-/-) influences the early stages of B lymphocyte development. Blood. 2010 Nov 11;116(19):3792-801
• All: 6 reference(s)