Farp2^tm1Akum
Targeted Allele Detail

Summary

• Symbol: Farp2^tm1Akum
• Name: FERM, RhoGEF and pleckstrin domain protein 2; targeted mutation 1, Atsushi Kumanogoh
• MGI ID: MGI:4847666
• Gene: Farp2 Location: Chr1:93439826-93549698 bp, + strand Genetic Position: Chr1, 47.24 cM
• Alliance: Farp2^tm1Akum page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166376
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Sequence spanning part of exon 9 through exon 10 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis. (J:166376)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Farp2 Mutation: 51 strains or lines available

References

• Original: J:166376 Takegahara N, et al., Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements. FASEB J. 2010 Dec;24(12):4782-92
• All: 1 reference(s)