Ahi1^tm1Xjl
Targeted Allele Detail

Summary

• Symbol: Ahi1^tm1Xjl
• Name: Abelson helper integration site 1; targeted mutation 1, Xiao-Jiang Li
• MGI ID: MGI:4849287
• Synonyms: Ahi1^loxp
• Gene: Ahi1 Location: Chr10:20828446-20956328 bp, + strand Genetic Position: Chr10, 9.75 cM, cytoband A3
• Alliance: Ahi1^tm1Xjl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166236
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129 x C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 2, and an additional loxP site was inserted downstream of exon 2. (J:166236)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ahi1 Mutation: 80 strains or lines available

References

• Original: J:166236 Xu X, et al., Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19126-31
• All: 3 reference(s)