Efna1^tm1Jinc
Targeted Allele Detail

Summary

• Symbol: Efna1^tm1Jinc
• Name: ephrin A1; targeted mutation 1, Jin Chen
• MGI ID: MGI:4849544
• Gene: Efna1 Location: Chr3:89179037-89188258 bp, - strand Genetic Position: Chr3, 39.04 cM
• Alliance: Efna1^tm1Jinc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166527
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis of P0 lung extracts. (J:166527)

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Efna1 Mutation: 18 strains or lines available

References

• Original: J:166527 Frieden LA, et al., Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1. Dev Dyn. 2010 Dec;239(12):3226-34
• All: 2 reference(s)