Dll1^m594592Hubr
Chemically induced Allele Detail

Summary

• Symbol: Dll1^m594592Hubr
• Name: delta like canonical Notch ligand 1; mutation 594592, Hubrecht Institute
• MGI ID: MGI:4849919
• Synonyms: 59459-2, Dll1^E26G, Dll1^m1Hubr
• Gene: Dll1 Location: Chr17:15587616-15597134 bp, - strand Genetic Position: Chr17, 8.95 cM
• Alliance: Dll1^m594592Hubr page

Shorter tail in Dll1^m594592Hubr/Dll1^m594592Hubr embryo

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

Allele Type: Chemically induced (ENU) Mutation: Single point mutation Mutation details: ENU mutagenesis induced a A to G transition that results in the amino acid substitution of glycine for glutamic acid at position 26 (E26G). (J:166883, J:173681) Inheritance: Recessive

An A-to-G mutation, localized in the N1 domain, causes a glutamine-to-glycine substitution in the Dll1^m594592Hubr mutant protein

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dll1 Mutation: 46 strains or lines available

References

• Original: J:166883 Meijlink F, Direct submission 2010/12/30_8FaPaB. MGI Direct Data Submission. 2010
• All: 3 reference(s)