Ptprb^m594684Hubr
Chemically induced Allele Detail

Summary

• Symbol: Ptprb^m594684Hubr
• Name: protein tyrosine phosphatase receptor type B; mutation 594684, Hubrecht Institute
• MGI ID: MGI:4849921
• Synonyms: 59468-4, Ptprb^m1Hubr, Ptprb^Y693X
• Gene: Ptprb Location: Chr10:116111428-116225440 bp, + strand Genetic Position: Chr10, 64.68 cM, cytoband D2
• Alliance: Ptprb^m594684Hubr page

Cardiac edema in a Ptprb^m594684Hubr/Ptprb^m594684Hubr embryo

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

Allele Type: Chemically induced (ENU) Mutation: Single point mutation Mutation details: ENU mutagenesis induced a T to A transversion that results in the amino acid substitution of a stop codon for tyrosine at position 693 (Y693X). (J:167035, J:173681) Inheritance: Recessive

Sequence analysis shows a T to A mutation in the Ptprb^m594684Hubr allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptprb Mutation: 99 strains or lines available

References

• Original: J:167035 Meijlink F, et al., Hubrecht Institute ENU screen. MGI Direct Data Submission. 2011
• All: 2 reference(s)