Plxnb2^m597804Hubr
Chemically induced Allele Detail

Summary

• Symbol: Plxnb2^m597804Hubr
• Name: plexin B2; mutation 597804, Hubrecht Institute
• MGI ID: MGI:4849926
• Synonyms: 59780-4, PlexinB2^E369G, Plxnb2^m1Hubr
• Gene: Plxnb2 Location: Chr15:89039752-89064960 bp, - strand Genetic Position: Chr15, 44.68 cM, cytoband E3
• Alliance: Plxnb2^m597804Hubr page

Exencephaly in Plxnb2^m597804Hubr/Plxnb2^m597804Hubr embryos

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

Allele Type: Chemically induced (ENU) Mutation: Single point mutation Mutation details: ENU mutagenesis induced an A to G transition that results in the amino acid substitution of glycine for glutamic acid at position 369 (E369G). (J:173681) Inheritance: Recessive

Sequencing reveals an A-to-G point mutation in the Plxnb2^m597804Hubr allele

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxnb2 Mutation: 88 strains or lines available

References

• Original: J:167035 Meijlink F, et al., Hubrecht Institute ENU screen. MGI Direct Data Submission. 2011
• All: 2 reference(s)