Zap70^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Zap70^m1Btlr
• Name: zeta-chain (TCR) associated protein kinase; mutation 1, Bruce Beutler
• MGI ID: MGI:4867219
• Synonyms: wanna, Zap70^H58R
• Gene: Zap70 Location: Chr1:36800912-36821899 bp, + strand Genetic Position: Chr1, 15.41 cM, cytoband A4-C1
• Alliance: Zap70^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The wanna mutation corresponds to an A to G transition position 264 (NM_009539) of the Zap70 transcript in exon 2 of 13 total exons. This changes the histidine at codon 58 to an arginine. (J:167119)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zap70 Mutation: 55 strains or lines available

References

• Original: J:167119 Beutler B, Direct Data Submission 2011/01/07. MGI Direct Data Submission. 2011
• All: 2 reference(s)