Smc1b^tm2.1Jess
Targeted Allele Detail

Summary

• Symbol: Smc1b^tm2.1Jess
• Name: structural maintenance of chromosomes 1B; targeted mutation 2.1, Rolf Jessberger
• MGI ID: MGI:4867229
• Synonyms: Smc1beta^fl
• Gene: Smc1b Location: Chr15:84948890-85016158 bp, - strand Genetic Position: Chr15, 40.25 cM, cytoband E3
• Alliance: Smc1b^tm2.1Jess page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166776
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 10, and an additional loxP site was inserted downstream of exon 10. Flp-mediated recombination removed the neo cassette leaving exon 10 floxed. (J:166776)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smc1b Mutation: 69 strains or lines available

References

• Original: J:166776 Revenkova E, et al., Oocyte cohesin expression restricted to predictyate stages provides full fertility and prevents aneuploidy. Curr Biol. 2010 Sep 14;20(17):1529-33
• All: 2 reference(s)