Lims2^tm1.1Chen
Targeted Allele Detail

Summary

• Symbol: Lims2^tm1.1Chen
• Name: LIM and senescent cell antigen like domains 2; targeted mutation 1.1, Ju Chen
• MGI ID: MGI:4867246
• Gene: Lims2 Location: Chr18:32055346-32091673 bp, + strand Genetic Position: Chr18, 17.89 cM
• Alliance: Lims2^tm1.1Chen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167114
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exons 3 and 4. The neo cassette remains intact. (J:167114)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lims2 Mutation: 20 strains or lines available

References

• Original: J:167114 Liang X, et al., Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality. Circulation. 2009 Aug 18;120(7):568-76
• All: 5 reference(s)