Khk^tm1.1Dtb
Targeted Allele Detail

Summary

• Symbol: Khk^tm1.1Dtb
• Name: ketohexokinase; targeted mutation 1.1, David T Bonthron
• MGI ID: MGI:4867311
• Synonyms: Khk^3a
• Gene: Khk Location: Chr5:31078780-31088592 bp, + strand Genetic Position: Chr5, 16.9 cM
• Alliance: Khk^tm1.1Dtb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166959
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Modified isoform(s))
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed the neo cassette. This allele is predicted to not produce isoform A. (J:166959)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Khk Mutation: 24 strains or lines available

References

• Original: J:166959 Diggle CP, et al., Both isoforms of ketohexokinase are dispensable for normal growth and development. Physiol Genomics. 2010 Nov 29;42A(4):235-43
• All: 1 reference(s)