Ednra^tm5Hku
Targeted Allele Detail

Summary

• Symbol: Ednra^tm5Hku
• Name: endothelin receptor type A; targeted mutation 5, Hiroki Kurihara
• MGI ID: MGI:4867385
• Synonyms: Ednra^EGFP
• Gene: Ednra Location: Chr8:78389658-78451081 bp, - strand Genetic Position: Chr8, 36.63 cM, cytoband C2
• Alliance: Ednra^tm5Hku page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166932
• Parent Cell Line: ATOM1 (ES Cell)
• Strain of Origin: (C57BL/6 x 129)F1

Mutation description

• Allele Type: Targeted (Null/knockout, RMCE-ready, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Using recombination mediated cassette exchange (RCME) the neo cassette in Ednra^tm1Hku was replaced with an EGFP cassette and an FRT flanked puromycin cassette. (J:166932)

Expression

In Mice Carrying this Mutation:	33 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ednra Mutation: 35 strains or lines available

References

• Original: J:166932 Asai R, et al., Endothelin receptor type A expression defines a distinct cardiac subdomain within the heart field and is later implicated in chamber myocardium formation. Development. 2010 Nov;137(22):3823-33
• All: 6 reference(s)