Tmf1^tm1Unir
Targeted Allele Detail

Summary

• Symbol: Tmf1^tm1Unir
• Name: TATA element modulatory factor 1; targeted mutation 1, Uri Nir
• MGI ID: MGI:4867389
• Gene: Tmf1 Location: Chr6:97129958-97156083 bp, - strand Genetic Position: Chr6, 44.89 cM
• Alliance: Tmf1^tm1Unir page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166798
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The 3' portion of exon 2 was replaced with a lacZ gene and floxed neo cassette. The absence of protein expression was confirmed by western blot on testis extracts. (J:166798)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmf1 Mutation: 45 strains or lines available

References

• Original: J:166798 Lerer-Goldshtein T, et al., TMF/ARA160: A key regulator of sperm development. Dev Biol. 2010 Dec 1;348(1):12-21
• All: 1 reference(s)