Rpe65^tvrm148
Chemically induced Allele Detail

Summary

• Symbol: Rpe65^tvrm148
• Name: retinal pigment epithelium 65; translational vision research model 148
• MGI ID: MGI:4867394
• Gene: Rpe65 Location: Chr3:159304812-159330958 bp, + strand Genetic Position: Chr3, 82.52 cM, cytoband H4
• Alliance: Rpe65^tvrm148 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A T-to-C point mutation results in an alteration of codon 229 from one encoding phenylalanine to serine. This codon is highly conserved in many species. (J:166679)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rpe65 Mutation: 52 strains or lines available

References

• Original: J:166679 Won J, et al., Mouse model resources for vision research. J Ophthalmol. 2011;2011:391384
• All: 3 reference(s)