Crx^tvrm65
Chemically induced Allele Detail

Summary

• Symbol: Crx^tvrm65
• Name: cone-rod homeobox; translational vision research model 65
• MGI ID: MGI:4867395
• Synonyms: Crx-L253X
• Gene: Crx Location: Chr7:15599872-15613880 bp, - strand Genetic Position: Chr7, 8.6 cM
• Alliance: Crx^tvrm65 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A T-to-A nonsense mutation in the last exon of the gene is predicted to alter the leucine 277 residue to a termination codon in the encoded protein. This mutation affects both known isofoms. (J:166679)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Crx Mutation: 27 strains or lines available

References

• Original: J:166679 Won J, et al., Mouse model resources for vision research. J Ophthalmol. 2011;2011:391384
• All: 5 reference(s)