Pdcd2^tm1Jcs
Targeted Allele Detail

Summary

• Symbol: Pdcd2^tm1Jcs
• Name: programmed cell death 2; targeted mutation 1, John C Schimenti
• MGI ID: MGI:4867683
• Gene: Pdcd2 Location: Chr17:15739472-15747560 bp, - strand Genetic Position: Chr17, 8.95 cM
• Alliance: Pdcd2^tm1Jcs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166618
• Parent Cell Line: v6.4 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced with a neo cassette via homologous recombination. (J:166618)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdcd2 Mutation: 15 strains or lines available

References

• Original: J:166618 Mu W, et al., PDCD2 is essential for inner cell mass development and embryonic stem cell maintenance. Dev Biol. 2010 Nov 15;347(2):279-88
• All: 1 reference(s)