Vps26b^tm1Ktch
Targeted Allele Detail

Summary

• Symbol: Vps26b^tm1Ktch
• Name: VPS26 retromer complex component B; targeted mutation 1, Kyu-Tae Chang
• MGI ID: MGI:4867701
• Gene: Vps26b Location: Chr9:26919067-26941361 bp, - strand Genetic Position: Chr9, 12.07 cM
• Alliance: Vps26b^tm1Ktch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167062
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 5 and flanking intronic sequences were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:167062)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vps26b Mutation: 20 strains or lines available

References

• Original: J:167062 Kim E, et al., Implication of mouse Vps26b-Vps29-Vps35 retromer complex in sortilin trafficking. Biochem Biophys Res Commun. 2010 Dec 10;403(2):167-71
• All: 2 reference(s)