Prkd1tm1.1Daca
Targeted Allele Detail
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Symbol: |
Prkd1tm1.1Daca |
Name: |
protein kinase D1; targeted mutation 1.1, Doreen A Cantrell |
MGI ID: |
MGI:4867731 |
Synonyms: |
PKD1(S744A/S748A), Prkd1SSAA |
Gene: |
Prkd1 Location: Chr12:50388014-50695881 bp, - strand Genetic Position: Chr12, 21.78 cM, cytoband C1
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Alliance: |
Prkd1tm1.1Daca page
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Germline Transmission: |
Earliest citation of germline transmission:
J:166867
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Not Applicable) |
Mutations: |
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Insertion, Nucleotide substitutions
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Mutation details: Exon 17 was replaced with a modified one in which nucleotide substitution results in the amino acid substitution of alanine for serine at positions 744 and 748 (S744A, S748A). A floxed neo cassette inserted downstream of the modified exon 17 was removed by cre-mediated recombination.
(J:166867)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Prkd1 Mutation: |
57 strains or lines available
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Original: |
J:166867 Matthews SA, et al., Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells. Biochem J. 2010 Oct 25;432(1):153-63 |
All: |
3 reference(s) |
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