Myb^boo
Chemically induced Allele Detail

Summary

• Symbol: Myb^boo
• Name: myeloblastosis oncogene; booreana
• MGI ID: MGI:4867909
• Gene: Myb Location: Chr10:21000834-21036883 bp, - strand Genetic Position: Chr10, 9.75 cM
• Alliance: Myb^boo page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation was identified in a screen of ENU mutations for hematopoietic system phenotypes. An A to G transition was identified at position 923 in exon 8. This results in a Glutamic acid to Glycine change of amino acid residue 308 affecting the transactivation domain. (J:167270)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Myb Mutation: 53 strains or lines available

References

• Original: J:167270 Papathanasiou P, et al., A recessive screen for genes regulating hematopoietic stem cells. Blood. 2010 Dec 23;116(26):5849-58
• All: 2 reference(s)