Myo9b^tm1.2Bah
Targeted Allele Detail

Summary

• Symbol: Myo9b^tm1.2Bah
• Name: myosin IXb; targeted mutation 1.2, Martin Bahler
• MGI ID: MGI:4867915
• Synonyms: Myo9b^-, Myo9b TypeI
• Gene: Myo9b Location: Chr8:71725358-71813357 bp, + strand Genetic Position: Chr8, 34.43 cM
• Alliance: Myo9b^tm1.2Bah page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162326
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutation: Intragenic deletion Mutation details: Exon 2 was removed by crossing Myo9b^tm1.1Bah mice with ZAP3-Cre-recombinase transgenic mice. Absence of protein was confirmed by western blot in spleen, thymus, and isolated immune cells. This is a null allele. (J:162326)

Generation of the Myo9b^tm1.1Bah and Myo9b^tm1.2Bah alleles

Expression

In Mice Carrying this Mutation:

15 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myo9b Mutation: 109 strains or lines available

References

• Original: J:162326 Hanley PJ, et al., Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motility. Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12145-50
• All: 5 reference(s)