Wdr36^tm1Erta
Targeted Allele Detail

Summary

• Symbol: Wdr36^tm1Erta
• Name: WD repeat domain 36; targeted mutation 1, Ernst R Tamm
• MGI ID: MGI:4868240
• Gene: Wdr36 Location: Chr18:32970241-33000008 bp, + strand Genetic Position: Chr18, 18.13 cM
• Alliance: Wdr36^tm1Erta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167354
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The first 16 exons were replaced with a lacZ and floxed neo cassette. (J:167354)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr36 Mutation: 43 strains or lines available

References

• Original: J:167354 Gallenberger M, et al., Lack of WDR36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro. Hum Mol Genet. 2011 Feb 1;20(3):422-35
• All: 2 reference(s)