Del(10Prmt2-Cstb)4Yah
Targeted Allele Detail

Summary

• Symbol: Del(10Prmt2-Cstb)4Yah
• Name: deletion, Chr 10, Yann Herault 4
• MGI ID: MGI:4868385
• Synonyms: Ms4Yah
• Gene: Del(10Prmt2-Cstb)4Yah Location: Chr10:76043060-78263456 bp Genetic Position: Chr10, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167505
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted
• Mutations: Intergenic deletion, Intragenic deletion
• Del(10Prmt2-Cstb)4Yah involves 81 genes/genome features (n-TAagc5, n-R5s77, Gm19376 ...) View all
• Mutation details: These mice were created using MICER targeting vectors. Prmt2 was targeted using a vector selected from the 3' HPRT library and the Cstb locus in cis was targeted using a vector selected from the 5' HPRT library. Mice carrying this construct were crossed with Tg(Zp3-cre)93Knw transgenic mice. Cre expression occurs during oogenesis in female mice from this cross and results in excision of a 2.2 MB segment of chromosome 10 containing 47 known genes. (J:167505)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Del(10Prmt2-Cstb)4Yah Mutation: 1 strain or line available

References

• Original: J:167505 Duchon A, et al., Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombination. Genetics. 2008 Sep;180(1):51-9
• All: 2 reference(s)