Ccr2^tm2.1Ifc
Targeted Allele Detail

Summary

• Symbol: Ccr2^tm2.1Ifc
• Name: C-C motif chemokine receptor 2; targeted mutation 2.1, Israel F Charo
• MGI ID: MGI:4868431
• Synonyms: Ccr2^R, Ccr2^RFP
• Gene: Ccr2 Location: Chr9:123901987-123913594 bp, + strand Genetic Position: Chr9, 75.05 cM, cytoband F
• Alliance: Ccr2^tm2.1Ifc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166664
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region was replaced with an RFP and floxed neo cassette. Cre-mediated recombination removed the neo cassette. The absence of transcript expression was confirmed by RT-PCR. (J:166664)

Expression

In Mice Carrying this Mutation:

4 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ccr2 Mutation: 43 strains or lines available

References

• Original: J:166664 Saederup N, et al., Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice. PLoS One. 2010;5(10):e13693
• All: 191 reference(s)