Tg(H2-K1-tsA58)6Kio
Transgene Detail

Summary

• Symbol: Tg(H2-K1-tsA58)6Kio
• Name: transgene insertion 6, Dimitris Kioussis
• MGI ID: MGI:4868476
• Synonyms: H-2K(b)-tsA58, immorto, Immortomouse, Tg(H2-K1-tsA58), Tg(H2K^b-tsA58)6Kio
• Transgene: Tg(H2-K1-tsA58)6Kio Location: unknown
• Alliance: Tg(H2-K1-tsA58)6Kio page

Transgene origin

• Strain of Origin: (CBA/Ca x C57BL/10)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The 5' flanking promoter and transcriptional start site of the mouse H-2Kb gene was fused to the SV40 tsA58 early region coding sequence. Thirty-four mice carrying from one to five copies of the transgene were born. Several lines were analysed including line 6 and 11. (J:126941)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:126941 Jat PS, et al., Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5096-100
• All: 60 reference(s)