Slc17a6^tm1.1Thna
Targeted Allele Detail

Summary

• Symbol: Slc17a6^tm1.1Thna
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1.1, Thomas Hnasko
• MGI ID: MGI:4879093
• Synonyms: Slc17a6^tm1.1Edw, VGLUT2^lox
• Gene: Slc17a6 Location: Chr7:51271754-51320867 bp, + strand Genetic Position: Chr7, 32.78 cM, cytoband B4
• Alliance: Slc17a6^tm1.1Thna page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167767
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv and C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 2 and an additional loxP site inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette leaving exon 2 floxed. (J:167767)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc17a6 Mutation: 60 strains or lines available

References

• Original: J:167767 Hnasko TS, et al., Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron. 2010 Mar 11;65(5):643-56
• All: 26 reference(s)