Napb^tm1Bros
Targeted Allele Detail

Summary

• Symbol: Napb^tm1Bros
• Name: N-ethylmaleimide sensitive fusion protein attachment protein beta; targeted mutation 1, Nils Brose
• MGI ID: MGI:4879973
• Synonyms: betaSNAP^-, Napb^tm1Rhee
• Gene: Napb Location: Chr2:148535905-148574387 bp, - strand Genetic Position: Chr2, 73.53 cM
• Alliance: Napb^tm1Bros page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167753
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:167753)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Napb Mutation: 25 strains or lines available

References

• Original: J:167753 Burgalossi A, et al., SNARE protein recycling by alphaSNAP and betaSNAP supports synaptic vesicle priming. Neuron. 2010 Nov 4;68(3):473-87
• All: 1 reference(s)